Effect of short-term orthokeratology lens or ordinary frame glasses wear on corneal thickness, corneal endothelial cells and vision correction in adolescents with low to moderate myopia

Shuyi Yuan,Shuxian Zhang,Yanglin Jiang,Lihua Li

doi:10.1186/s12886-019-1222-y

Effect of short-term orthokeratology lens or ordinary frame glasses wear on corneal thickness, corneal endothelial cells and vision correction in adolescents with low to moderate myopia

Shuyi Yuan, Shuxian Zhang + Show 2 more

Open Access

https://doi.org/10.1186/s12886-019-1222-y

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Abstract

BackgroundWe aimed to investigate the effect of short-term orthokeratology lens or frame glasses wear on corneal thickness, corneal endothelial cells and vision correction in adolescents with low to moderate myopia.MethodsData of 100 adolescents with low to moderate myopia were retrospectively analyzed. The patients were assigned into two groups. The experimental group were treated with night-wear orthokeratology lens, and control group were treated with ordinary frame glasses. Follow up was carried out at the 3rd, 6th and 12th months of treatment. The naked-eye vision, diopter, corneal curvature, intraocular pressure, axial length, endothelial cell count and central corneal thickness were examined. Complications within 12 months were observed, and corneal fluorescein staining was graded.ResultsThe naked-eye vision of the experimental group was significantly higher than that of the control group at the 3rd, 6th and 12th months, while the diopter of the experimental group was significantly lower than that of the control group at these time points. The corneal curvature of the experimental group was significantly decreased when comparing with that of the control group at the above 3 time points. The increase of axial length in the experimental group was significantly less than that in the control group at the 6th and 12th months.ConclusionsShort-term orthokeratology lens wear can effectively improve the naked-eye vision in adolescents with low to moderate myopia without significant impact on the central corneal thickness and corneal endothelial cells. It is a relatively safe method to correct myopia.

Highlights

We aimed to investigate the effect of short-term orthokeratology lens or frame glasses wear on corneal thickness, corneal endothelial cells and vision correction in adolescents with low to moderate myopia
Naked-eye vision and diopter It was found that the naked-eye vision of patients increased gradually in the experimental group, while decreased gradually in the control group
The diopter gradually decreased in the experimental group, while gradually increased in the control group, and was Control group Experimental group (n = 94)

Summary

Introduction

We aimed to investigate the effect of short-term orthokeratology lens or frame glasses wear on corneal thickness, corneal endothelial cells and vision correction in adolescents with low to moderate myopia. There are many studies on myopia, its pathogenesis is still unclear. Most studies indicate that myopia is related to genetic. A few dots of staining No Treatment I. Increased spots showing a Continuing lens wear and scatter pattern using a small amount of eye II obvious clinical manifestations, dense and diffuse spots drop for cornea repair until the disappearance of symptoms III. A large number of stippling Stopping treatment, adjusting stains, aggregation and fusion the lens, and giving occurred in a large range symptomatic medication until IV

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