Abstract

The effect of Shengmaisan (SMS) on coronary heart disease (CHD) patients, 30 angina pectoris and 68 acute myocardial infarction (AMI) and its peroxidation damage was studied. It was shown that the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in blood decreased and the content of malondialdehyde (MDA) in plasma increased in CHD patients in comparison with the healthy controls (P 0. 05). It could be assumed that the pathogenesis of CHD is associated with free radical (FR) triggering a chain reaction of the lipid peroxidation, and that SMS is acting as an effective free radical scavenger, which would ameliorate the lipid peroxidation damage. Thus, SMS could be administered in the prevention and the treatment of CHD.

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