Effect of shenfu injection on ultrasound cardiogram in patients of acute myocardial infarction combined with pump failure

Abstract

Objective To study the clinical effect of shenfu injection on ultrasound cardiogram in patients of acute myocardial infarction combined with pump failure.Methods Eighty patients with acute myocardial infarction combined with pump failure were divided into control group and experiment group by random digits table method with 40 cases each.The patients in control group received common drug treatment,and the patients in experiment group received common drug combined with shenfu injection treatment.The clinical effect and the change of ultrasound cardiogram after treatment were compared between the 2 groups.Results The total effective rate in experiment group was significantly higher than that in control group [82.5％ (33/40) vs.50.0％ (20/40)],and there was statistical difference (P ＜ 0.05).The results of ultrasound cardiogram showed there were no statistical differences in peak E velocity,left ventricular ejection fraction,left ventricular fractional shortening and E/A before treatment between the 2 groups (P ＞0.05),and the indexes were significantly improved after treatment compared with those before treatment.Furthermore,the indexes in experiment group were significantly better than those in control group [(0.87 ± 0.18) m/s vs.(0.65 ± 0.22) m/s,(51.0 ± 10.2)％ vs.(43.9 ± 12.1)％,(27.5 ± 6.5)％ vs.(22.5 ± 5.3)％,0.86 ±0.18 vs.0.76 ±0.13],and there were statistical differences (P ＜0.05).Conclusion Shenfu injection may play an important role in improving prognosis,decreasing mortality for patients with acute myocardial infarction combined with pump failure. Key words: Myocardial infarction; Shenfu injection; Pump failure