Abstract

Serum concentrations of protein precipitable iodine were determined both before and after elution from a Dowex-1 resin anion exchange column in 50 adolescent boys and 46 adolescent girls between the ages of 10 and 18 years. All subjects were well and in excellent nutritional status. Each subject received careful physical examination, during which sexual maturation was estimated, and each child was given a maturity rating of from 1 to 5. Attempted correlation of the peripheral concentration of hormonal iodine, done by two methods with individual maturity ratings, demonstrated a decrease in these values with increasing maturity in boys; the lowest iodine values were found during the period of the greatest rate of increase in sexual maturation.

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