Abstract
Meeting Abstracts1 May 1973Effect of Serum Potassium Level upon Risk of Digitalis Toxicity.Roger W. Jelliffe, M.D., F.A.C.P.Roger W. Jelliffe, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-78-5-821_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBecause hypokalemia predisposes to digitalis toxicity, the relationships between computed total body glycoside concentration (C) (derived from previously described computer programs), serum potassium levels (K), and the cumulative incidence of digitalis toxicity (T) were examined in 79 patients who did not receive computer-assisted therapy. Seventy-two patients had received digoxin; 7 received other preparations. Glycoside concentration was highly correlated with serum digoxin levels (L) : L = 0.185C -0.416 (P < 0.001). Toxicity was defined as nausea, vomiting, or any new arrhythmia that improved or disappeared when digitalis was stopped.Forty-six patients (58%) had no toxicity; their glycoside concentration averaged 15.4... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIndividualizing Digoxin TherapyThe Present and Future State of Individualized TherapyPrefaceDigoxin Level and Clinical Manifestations as Determinants in the Diagnosis of Digoxin ToxicityClinical Applications of Pharmacokinetics and Control Theory: Planning, Monitoring, and Adjusting Dosage Regimens of Aminoglycosides, Lidocaine, Digitoxin, and DigoxinComputer-controlled administration of cardiovascular drugsThe serum digoxin test and digoxin toxicity: a Bayesian approach to decision making.PLASMA POTASSIUM LEVELS IN HYPERTENSIVE PATIENTS RECEIVING FIXED‐COMBINATION DIURETIC THERAPYCapturing clinical expertiseA nomogram for digoxin therapy 1 May 1973Volume 78, Issue 5Page: 821-821KeywordsArrhythmiaAttentionGlycosidesNauseaPotassiumSoftware toolsToxicityVomiting Issue Published: 1 May 1973 PDF downloadLoading ...
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