Effect of Sasa borealis bamboo Diet on Lipid Levels, Platelet Aggregation and Erythrocyte Na+ Efflux in OLETF Rats

Abstract

This study was conducted to investigate the effects of Sasa borealis bamboo leaves on plasma and liver lipids, platelet aggregation and erythrocyte Na efflux using OLETF rats. OLETF and the normal counterpart LETO rats were divided two groups each and fed either control diet or diet with 10% Sasa borealis bamboo leaves for four weeks.The final weight with high FER were significantly increased in OLETF rats (p<0.05). Plasma and liver total cholesterol and TG were significantly increased in OLETF rats compared with LETO rats (all, p<0.05). Plasma total cholesterol and TG in OLETF‐bamboo was significantly decreased compared with OLETF‐control (p<0.05, p<0.01). HDL‐cholesterol was significantly lower and blood glucose was significantly higher in OLETF than LETO rats (p<0.05, respectively). Platelet aggregation in initial slope was significantly decreased in OLETF rat (p<0.05), and bamboo reversed it. Intracellular Na was significantly increased in OLETF rats and bamboo diet significantly decreased (p<0.05). Na‐K ATPase and Na‐K cotransport tended to be lower and Na passive transport be higher in OLETF than LETO rats, and bamboo diet significantly decreased Na‐K cotransport in LETO and OLETF rats (p<0.05). Liver TBARS production decreased significantly in OLETF fed bamboo compared with OLETF‐control (p<0.05).In present study, OLETF rats, type II DM model showed unfavorable parameters in terms of weight gain and blood and liver lipids, and hypolipidemic and antioxidant effects of Sasa borealis bamboo were more evident in OLETF rats.