Abstract
ObjectiveTo investigate the effect of remifentanil-based fast-track anesthesia on analgesia and sedation after transthoracic device closure of ventricular septal defects (VSDs) in adult patients.MethodsA retrospective analysis was performed on 59 patients aged 21–53 years who underwent transthoracic device closure of VSDs from January 2019 to September 2019. According to the different anesthesia strategies, the patients were divided into the R group (using remifentanil-based anesthesia, n = 33) and the S group (using sufentanil-based anesthesia, n = 26). Patient-related clinical data, postoperative analgesia, and sedation scores were collected and analyzed.ResultsThere was no significant difference in age, gender, body weight, and operation time between the group R and the group S (P > 0.05). There was also no significant difference in intraoperative hemodynamic changes, BIS scores, postoperative analgesia, and sedation scores between the two groups (P > 0.05). The duration of mechanical ventilation, the length of ICU stay, and hospital stay in the group R were significantly lower than those in the group S (P < 0.05).ConclusionRemifentanil-based fast-track anesthesia is effective for adult patients undergoing transthoracic device closure of VSDs, which may shorten the mechanical ventilation duration, the ICU and hospital stay of patients.
Highlights
Ventricular septal defect (VSD) is one of the most common congenital heart diseases requiring surgical correction
In order to meet the needs of short anesthesia time and early tracheal extubation after transthoracic device closure of VSDs, fast-track anesthesia was adopted in our cardiac center
This study aimed to investigate the effect of remifentanil-based fast-track anesthesia on analgesia and sedation after transthoracic device closure of VSDs under transesophageal guidance echocardiography (TEE) in adult patients
Summary
Ventricular septal defect (VSD) is one of the most common congenital heart diseases requiring surgical correction. The main treatment methods are traditional surgical repair, percutaneous device closure, and transthoracic device closure. Traditional surgical repair has a wide range of indications, it is combined with the following deficiencies: large incision and trauma, low aesthetic effect, long operation time and hospital stay, high risk of postoperative complications, etc. In order to meet the needs of short anesthesia time and early tracheal extubation after transthoracic device closure of VSDs, fast-track anesthesia was adopted in our cardiac center. Fast-track anesthesia has been applied and studied in adult congenital heart disease surgery in many countries. This study aimed to investigate the effect of remifentanil-based fast-track anesthesia on analgesia and sedation after transthoracic device closure of VSDs under transesophageal guidance echocardiography (TEE) in adult patients
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