Abstract
Purpose The effect of red light rhinophototherapy (RLRPT) on nasal patency in patients with a clinical diagnosis of allergic rhinitis was investigated. Materials and Methods Subjects were randomly divided into 2 groups, with patients in one group given one treatment session of RLRPT, followed by medical treatment. Those in the second group were treated with medical treatment only. The rhinitis symptoms were evaluated both before and 30 minutes after RLRPT and 2 days later. The nasal patency was objectively measured through the use of both active anterior rhinomanometry and acoustic rhinometry before and 30 minutes after RLRPT. Results All rhinitis symptoms, including nasal congestion, significantly improved 30 minutes after a single RLRPT treatment, but worsened again, particularly for sneezing, 2 days later. Nasal resistance slightly decreased 30 minutes after RLRPT. The first minimal cross-sectional area did not change after RLRPT, but the second minimal cross-sectional area with the volume of the nasal cavity between 2.0 and 5.0 cm from the tip of the nosepiece significantly lessened. Conclusions This study showed that RLRPL did not objectively improve patient's nasal patency. Registration Number The trial is registered with NCT03752645.
Highlights
Rhinophototherapy has been used to treat both allergic rhinitis (AR) and chronic rhinosinusitis [1, 2]
Sixty patients with a clinical diagnosis of allergic rhinitis were enrolled between March and June of 2018
Rhinophototherapy has been recommended into the ARIA guidelines for those patients with allergic rhinitis who do not respond to standard medical treatment [11]
Summary
Rhinophototherapy has been used to treat both allergic rhinitis (AR) and chronic rhinosinusitis [1, 2]. One device emits a visible red light at a single wavelength of 660 nm (red light rhinophototherapy, RLRPT). One study has shown that after the nasal cavity was illuminated using a lowenergy narrow-band red light three times a day for 14 days, the symptoms and endoscopic findings in patients with allergic rhinitis improved significantly [1]. When the mechanism of rhinophototherapy is not fully understood, a low-energy narrow-band light illumination has been claimed to have biochemical, cellular, histological, and functional effects [1]. The effect of rhinophototherapy on the nasal patency has not yet been fully investigated. We attempted to investigate the short-term effects of RLRPT on nasal patency in patients with a clinical diagnosis of AR using both active anterior rhinomanometry and acoustic rhinometry
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