Abstract
Substances facilitating a self-stimulation response (amphetamine, cocaine, caffeine, morphine, benactyzine, phenobarbital, meprobamate, diazepam, chloridiazepoxide) and also electrical stimulation of systems of positive brain reinforcement, accelerate the development of ability of rats to pass through a maze. Amphetamine, cocaine, caffeine, morphine, benactyzine, phenobarbital, and electrical stimulation of the positive reinforcement systems increase the duration of forced swimming of the animals. Meprobamate, diazepam, and chlordiazepoxide have no effect on this parameter. It is postulated that the ability of psychotropic drugs to activate positive reinforcement systems is linked with their action on the capacity for mental and physical work.
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