Abstract

SummaryMouse monocytes, induced by intraperitoneal injection of mineral oil, produced lactate from only glucose and fructose. No net lactate production was noted from 29 other sugars. In vivo infection of monocytes resulted in at least a 2-fold increase in lactate production. However, no effect was noted when either heat-killed Pseudomonas aeruginosa or sonic fractions thereof were added to monocytes in vitro. No significant differences in lactate production were noted between cells obtained from immunized and non-immunized animals.

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