Abstract
The globulin fraction from both redgram ( Cajanus cajan) and horsegram ( Dolichos biflorus) has a hypolipidaemic action in rats fed a high-fat-high-cholesterol diet. Total and free cholesterol, phospholipids and triglycerides in the serum, liver and aorta of rats receiving the globulin fraction were much lower than in the high-fat-high-cholesterol fed controls. The redgram fraction showed more hypolipidaemic activity than that from horsegram, but less than that of the protein fraction from blackgram reported earlier. The insoluble polysaccharide fraction from both had no lipid-lowering effect, unlike that from blackgram. The globulin fraction from both contained a carbohydrate residue which was heterogeneous on acrylamide gel electrophoresis.
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