Abstract
To study the effect of protein deficiency on collagen cross-Unking in albino-rat skins and granulomas, two groups of weanling albino rats were raised for 3 weeks with normal and low protein diets by paired-feeding technique. The analysis of skins showed α<sub>1</sub>and α<sub>2</sub>-chain subunits of neutral salt-soluble collagen appreciably increased, <i>β<sub>11</sub></i>- and <i>β<sub>12</sub></i>-chains and the aldehyde content significantly decreased whereas the solubility of insoluble collagen in <i>KCNS</i>, urea or pronase increased greatly in protein-deficient animals compared to controls. The gel reversibility of neutral salt-soluble collagen increased in both skins and granulomas of protein-deficient animals compared to controls. The results indicate that in protein deficiency the cross-linking and maturation of collagen are impaired.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
