Abstract
A prospective bacteriological study was carried out on 84 patients admitted to hospital with a diagnosis of primary pneumonia. Of the 76 (90%) patients with radiological evidence of consolidation, only 22 (29%) had sputum samples that produced Streptococcus pneumoniœ or Hœmophilus influenzœ. None of these 22 patients had received previous antimicrobial therapy. Of the 52 patients who had received previous therapy, 36 (69%) produced no potential pathogens and 15 (29%) produced "coliform" bacilli on sputum culture. No patients in this group had Str. pneumoniœ or H. influenzœ isolated from their sputum. In most cases therapy was only begun after admission to hospital. Clearly, the simple concept of obtaining specimens before starting therapy is difficult to apply.
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