Abstract
Objective: To analyze the effect of preoperative depression on early postoperative cognitive function after general anesthesia during laparoscopic colon cancer surgery. Methods: One hundred and fifty ASA Ⅰ-Ⅱ general aneasthesia patients (male70, female 80)from Sir Run Run Shaw Hospital in May of 2015 to April of 2016, aged 50-85, undergoing selective laparoscopic colon cancer patients were included. Evaluated preoperative depression by self-rating depression scale and evaluated postoperative cognitive function on 1, 3, 7 days by post-operative quality recovery scale. Use the multi-factor logistic regression to select the risk factors. Results: There were 115 (76.7%) patients occurred poor cognitive function. According to SDS, The results of logistic regression analysis showed that the risk factors for postoperative poor cognitive function was severe depression(OR 1.295, 95% CI 1.012-13.184, P=0.048). Conclusion: Preoperative severe depression is a risk factor on postoperative cognitive function in laparoscopic colon cancer patients during general anesthesia.
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