Abstract
Background. Due to the effect of pre-heating on the degree of conversion of composite resins and the possible effect on cytotoxicity, the effect of pre-heating of bulk-fill composite resins was investigated on cytotoxicity in this study. Methods. In this study, three different types of composite resin were used, including Tetric N-Ceram Bulk-Fil, Xtrafil, and Xtrabase. From each composite resin, 10 cylindrical samples (5 mm in diameter and 4 mm in height) were prepared, with five samples preheated to 68°C, and the other five samples polymerized at room temperature (25°C). Twenty-four hours after polymerization, cytotoxicity was assessed by MTT assay on human fibroblasts. Statistical analysis of data was carried out with two-way ANOVA and Sidak Post-Hoc. The significance level of the test was determined at 0.05. Results. There was no statistically significant difference between the mean percentage of cytotoxicity in terms of pre-heating (P>0.05), but the cytotoxicity of the studied composite resins was significantly different (P<0.001). The cytotoxicity of Tetric N-Ceram Bulk-fil composite resin was higher than that of the two other composite resins. Conclusion. Pre-heating of bulk-fill composite resin did not affect their cytotoxicity. In addition, the cytotoxicity of different bulk-fill composite resins was not the same.
Highlights
Composite resins are extensively used as restorative materials in dentistry due to their esthetic, handling characteristics, and controlled working time.[1]
Due to the effect of pre-heating on the degree of conversion of composite resins and the possible effect on cytotoxicity, the effect of pre-heating of bulk-fill composite resins was investigated on cytotoxicity in this study
10 cylindrical samples (5 mm in diameter and 4 mm in height) were prepared, with five samples preheated to 68°C, and the other five samples polymerized at room temperature (25°C)
Summary
Composite resins are extensively used as restorative materials in dentistry due to their esthetic, handling characteristics, and controlled working time.[1] If the polymerization of composite resins is not adequate, the unreacted monomers remaining in the structure of composite resin might be released into the oral environment after mechanical and chemical degradation during the clinical service.[2]. Even immediately after placing composite resin restorations, monomers have been found in the saliva, dentin, and pulp.[3] These monomers have side effects such as skin, mucous membranes, and eye irritation.[4] In the oral cavity, lichenoid reactions have been. JODDD, Vol 14, No 1 Winter 2020 reported around composite resin restorations.[5] Van Dijken et al[6] reported that gingival exudate around the healthy enamel was less than that of composite resin restorations in seven days. Due to the effect of pre-heating on the degree of conversion of composite resins and the possible effect on cytotoxicity, the effect of pre-heating of bulk-fill composite resins was investigated on cytotoxicity in this study
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