Abstract
Objective To investigate the effect of preemptive analgesia on postoperative cognitive function in elderly patients with abdominal surgery. Methods Totals of 127 cases of elderly patients with open major surgery were randomly divided into two groups： the experimental group （63 cases） and the control group （64 cases）. The patients underwent preemptive analgesia in the experimental group, while the control group underwent conventional analgesia. VAS and MMSE were used to compare their pain and cognitive function between two groups, and dosages of fentanyl and adverse reactions were also observed. Results There were finally 60 cases in each group who had finished the study. The pain score was （ 1. 86±0. 62 ） in the experimental group and （4.03±0.48 ） in the control group six hours after operation, with statistically significant difference （ t = 3.67, P 〈 0.0）. The score of cognitive function was （25.42 ± 0.63 ） in the experimental group and （21.77± 0.50） in the control group 24 hours after operation, and the difference was statistically significant （t = 3.54, P 〈 0.05 ）. The dosages of fentanyl was （597.94±82.41 ） μg in the experimental group and （ 826.47± 113.28 ） μgin the control group, with statistically significant difference （ t = 5.42, P 〈 0.01 ）. The incidence of POCD was 20.00% in the experimental group and 38.33% in the control group, and the difference was statistically significant （X^2 = 3.03,P 〈 0.05）. Conclusions Preemptive analgesia of electroacupunctnreon elderly patients with abdominal surgery can significantly reduce their postoperative pain and improve cognitive dysfunction. Key words: Electroacupuncture ; Pain; Elderly; Preemptive analgesia; Cognitive function
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