Abstract

The effect of changes in posture, i.e. from supin e to upright position, on internal carotid artery (ICA) blood flow in conscious man was studied with the aid of electromagnetic flowmetry. A flow probe was implanted on the ICA in 23 patients after carotid reconstruction. ICA mean blood flow and brachial artery mean blood pressure were continuously monitored in 25 tilting tests and arterial carbon dioxide tension (PaCO2) was studied in 11/25. Cardiac output was measured in supine and upright position in 9/25 tilting tests. the patients (24/25) reacted to orthostatic blood shifts with a markedly hypokinetic circulation and a high incidence of fainting (6/25) in upright position.In 19 studies on non-fainting patients, ICA flow decreased in upright position in average by 25 % below supine control flow within one minute. ICA flow then gradually declined to a level 30% below control flow in supine position within five minutes. PaCO, decreased at the same time in average by 4 mmHg and the brachial artery pressur...

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