Abstract
Mechanical properties of extracellular matrix (ECM)- a complex viscoelastic medium in which biological cells reside- is known to dictate a variety of cell behavior and functions, including cell adhesion, growth, motility, intercellular communication and differentiation. The direct consequence of the mechanical properties of the ECM on cell behavior has attracted tremendous interest in tissue engineering to design polymeric scaffolds mimicking the topology and rheological behavior of the native extracellular microenvironment.
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