Effect of pleural effusion on gas exchange and response to positive end-expiratory pressure in acute lung injury/acute respiratory distress syndrome patients

D Chiumello,L Gattinoni,C Mietto,M Lazzerini,M Cressoni,V Berto

doi:10.1186/cc7203

Abstract

Pleural effusion is a common finding in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) patients. However, the effect of pleural effusion on gas exchange, respiratory mechanics and response to positive end-expiratory pressure (PEEP) in ALI/ARDS patients, during mechanical ventilation, has never been prospectively studied.

Highlights

There is considerable uncertainty about the reproducibility of the various instruments used to measure dyspnea, their ability to reflect changes in symptoms, whether they accurately reflect the patient’s experience and if its evolution is similar between acute heart failure syndrome patients and nonacute heart failure syndrome patients
Results of this study show that early tracheostomy, if perioperative complications
We looked at the use of postwith tracheostomies performed in the critical care unit of a tertiary procedure chest radiography (CXR)

Summary

Introduction

There is considerable uncertainty about the reproducibility of the various instruments used to measure dyspnea, their ability to reflect changes in symptoms, whether they accurately reflect the patient’s experience and if its evolution is similar between acute heart failure syndrome patients and nonacute heart failure syndrome patients. Conclusions Our data demonstrate that critically ill patients may be exposed to a higher FiO2 than that required to maintain adequate oxygenation These results highlight an area of ICU care that has received little study, with no published clinical trials examining the effect of FiO2 on outcome. Results Age, sex, the underlying disease and tumour stage (TNM classification), type of previous anticancer treatment, performance status, severity scores (APACHE II, Simplified Acute Physiology Score II, Sequential Organ Failure Assessment), ICU and hospital mortalities and hospital outcome at 3, 6 and 12 months were analysed. Clinical data of 277 post-transplantation patients admitted to the ICU were collected at admission and the SAPS 3 and APACHE II score calculated with respective estimated mortality rates.

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