Effect of platelet rich plasma on stability of dental implants: A prospective comparative clinical study

Abstract

Background: Good implant stability is the prime concern for successful prosthetic rehabilitation. Many methods and different types of implants have been used to achieve primary and secondary stability with varying success rates. The evolution continued with the use of biological materials for early osseointegration. The present study was aimed to compare and evaluate the effect of platelet rich plasma (PRP) on the early osseointegration and secondary stability of dental implants using implant stability values. Materials and Methods: A total of 18 dental implants were randomly placed among 10 patients in the mandibular posterior region using split mouth design. In the control group, implants were placed following standard surgical protocol. In the study group, autologous PRP was used to moisten the implants before placement. Implant stability was observed and compared using Osstel Implant stability meter at 0, 30, 60, and 90 days. All the cases were followed-up over period of 18 months. Statistical analysis was carried using one-way analysis of variance and paired and unpaired t-test. Results: Significant difference in stability values were observed in the study group following 30 days after implant placement. Control group showed no statistically significant difference at all time intervals. Implant stability values were higher in the early phase of osseointegration in the PRP group. However, at the end of the study period, both groups showed similar stability. Conclusion: Good primary implant stability is beneficial for early loading and rehabilitation. PRP can be successfully used as an adjunct for better and early function. It is safe due to its autologous origin, thus eliminating the risk of disease transmission and immunogenic reactions.