Abstract
The effects of several plasticizers on the following properties of cellulose acetate phthalate films were studied: water vapor transmission rate, moisture absorption, enteric coating performance (minimum coating required on tablets to prevent gastrodisintegration), tablet‐disintegration time, and water permeation. The addition of plasticizers generally lowered the water vapor transmission rate, moisture absorption, and water permeation but had little effect on tablet‐disintegration time. However, addition of most plasticizers resulted in poorer enteric coating performance. Significant differences among the plasticizers were observed, and no one plasticizer was found to be superior overall.
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