Abstract

Objective:To evaluate the effects of percutaneous pigtail catheter drainage on the outcomes of intracytoplasmic sperm injection (ICSI) pregnancies following moderate or severe ovarian hyperstimulation syndrome (OHSS).Materials and Methods:This retrospective study included 189 patients hospitalized for OHSS following ICSI treatment in a tertiary in vitro fertilization unit between 2006 and 2014. Pigtail catheters were applied in 63 patients; the other 126 patients did not need that treatment. The obstetric reports of 173 patients could be accessed and were examined to investigate the pregnancy outcomes of those with and without catheters.Results:No complications such as infection or vascular or intra-abdominal organ trauma were observed related to the pigtail application. There were no differences in abortus, preterm labor, gestational diabetes mellitus, and preeclampsia ratio between the pigtail and control groups (p>0.05). The rate of readmission to hospital for OHSS was lower in the pigtail group than in the control group although not statistically significant (p=0.08).Conclusion:Pigtail application is a safe and effective method for draining ascites in patients with OHSS after ICSI treatment. The use of pigtail catheters had no adverse effects on the perinatal outcomes of patients hospitalized with OHSS who became pregnant after ICSI treatment. In addition, the percutaneous drainage of ascites via a pigtail catheter helped prevent the readmission of patients with moderate or severe OHSS.

Highlights

  • Ovarian hyperstimulation syndrome (OHSS) is a serious and sometimes life-threatening complication of in vitro fertilization (IVF) treatment

  • The use of pigtail catheters had no adverse effects on the perinatal outcomes of patients hospitalized with ovarian hyperstimulation syndrome (OHSS) who became pregnant after intracytoplasmic sperm injection (ICSI) treatment

  • We evaluated the obstetric outcomes of patients who experienced an IVF/intracytoplasmic sperm injection (IVF/ICSI) pregnancy following OHSS, and compared patients with and without pigtail catheters

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Summary

Introduction

Ovarian hyperstimulation syndrome (OHSS) is a serious and sometimes life-threatening complication of in vitro fertilization (IVF) treatment. Various preventive measures are taken, the incidence of OHSS is still around 2%(1), and management plays an important role in this potentially lethal complication. There are no OHSS-free clinics, there are preventive measures such as freeze-all protocols and lower ovarian stimulation IVF protocols. Pigtail catheters have proven to be safe for draining ascites fluid. It is not clear whether this invasive procedure creates any procedure-related risk for pregnant patients such as bleeding, infection, trauma to neighbouring intraabdominal organs or preterm delivery. We evaluated the obstetric outcomes of patients who experienced an IVF/intracytoplasmic sperm injection (IVF/ICSI) pregnancy following OHSS, and compared patients with and without pigtail catheters

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