Abstract
Physical exercise has been proposed as a new alternative to chemical adjuvants. To investigate the relationship between regular exercise and post-vaccination antibody response in the elderly. The study was conducted with the elderly over the age of 65. 30participants we randomized into 2groups and divided into exercise and control groups. The experimental group received a 12-week exercise program. The control group was followed up without any exercise. The day on which the second dose of the vaccine was administered to all participants was considered day 0. The antibody level in the serum samples was taken 15days and 12weeks after the vaccination. The antibody concentration was measured after the second dose of vaccination. The mean antibody level in the control group was 69.4U/ml and 56.4U/ml 15days and 12weeks after the second vaccination. The mean antibody level in the exercise group was 74U/ml and 71.6U/ml 15days and 12weeks after the second vaccination. Regular exercise of light to moderate intensity may increase post-vaccination antibody response in the elderly. Therefore, exercise can be used as a behavioral adjuvant to improve the vaccine efficacy in the elderly.
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