Abstract

An experiment was conducted to determine if pharmacological concentrations of copper (Cu) affect lipid and cholesterol metabolism in Cu-adequate pigs. Treatments consisted of: control (10 ppm Cu as cupric sulfate, CuSO 4); control + 66 or 225 ppm Cu as CuSO 4; control + 33, 66, or 100 ppm Cu as cupric citrate (CuCit). Pigs were fed their respective diets throughout the nursery (35 d) and growing-finishing (GF; 103 d) phases. Copper increased (P < .05) serum cholesterol during the nursery phase, but 100 ppm CuCit decreased (P < .05) serum cholesterol relative to the control on d 42 of the GF phase. Serum triglycerides were increased (P < .05) by 225 ppm CuSO 4 relative to the control on d 42 of the GF phase. Percent lipid and cholesterol concentrations of the semitendinosus muscle were not affected by Cu. Lipid percentage of the longissimus muscle was decreased (P < .06) by 225 ppm CuSO 4 compared to the control, but Cu did not affect cholesterol concentration or fatty acid profile. These results indicate that pharmacological concentrations of Cu have little effect on cholesterol and lipid metabolism in the Cu-adequate pig.

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