Abstract
Both periodontal disease and diabetes are common chronic inflammatory diseases. One of the major problems with type 2 diabetes is that unregulated blood glucose levels damage the vascular endothelium and cause complications. A bidirectional relationship between periodontal disease and diabetic complications has been reported previously. However, whether periodontal disease affects the presence of diabetic complications has not been clarified. Therefore, we examined the effect of the periodontal disease status on diabetic complications in patients with type 2 diabetes. Periodontal doctors examined the periodontal disease status of 104 type 2 diabetic patients who visited a private diabetes medical clinic once a month between 2016 and 2018. The subject’s diabetic status was obtained from their medical records. Bayesian network analysis showed that bleeding on probing directly influenced the presence of diabetic retinopathy in type 2 diabetes patients. In addition, bleeding on probing was higher in the diabetic retinopathy group (n = 36) than in the group without diabetic retinopathy (n = 68, p = 0.006, Welch’s t-test). Bleeding on probing represents gingival inflammation, which might affect the presence of diabetic retinopathy in type 2 diabetes patients who regularly visit diabetic clinics.
Highlights
Both periodontal disease and type 2 diabetes are known to be common chronic inflammatory diseases [1,2]
It has been reported that hemoglobin A1c (HbA1c) levels are reduced when type 2 diabetic patients are treated for periodontal disease [8,9,10]
It was reported that when blood glucose was controlled in type 2 diabetic patients, the bleeding on probing (BOP) value, which represents the inflammation state of periodontal disease, improved [11]
Summary
Both periodontal disease and type 2 diabetes are known to be common chronic inflammatory diseases [1,2]. Many studies have reported a bidirectional relationship between periodontal disease and type 2 diabetes [3,4,5]. It was reported that when blood glucose was controlled in type 2 diabetic patients, the bleeding on probing (BOP) value, which represents the inflammation state of periodontal disease, improved [11]. Both periodontal disease and type 2 diabetes have a high prevalence worldwide [12]; the mechanism underlying the bidirectional relationship between them remains unclear
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
