Abstract

Pepper fruit (Dennetia tripetala) is a well-known forest fruit from the familyAnnonacea and has been found to contain lots of minerals, vitamins, alkaloids andtrace elements which are of medicinal importance. Studies have shown that pepperfruit contains stimulants. Stimulants affect the nervous system. This study therefore,was aimed at investigating the effect of pepper fruit on tear production. Fortyvolunteers of age between 18-30 years were used. The tear volume of eachindividual was measured before and after ingestion of 1.25g of pepper fruit usingschirmers strip. The measurement after ingestion of pepper fruit was done at 30minutes, 60 minutes and 90 minutes. The mean baseline tear production was 25.85± 8.7mm (± Standard deviation) and the mean change in tear production after 30, 60and 90 minutes interval was 22.73 ± 10.46mm, 19.50 ± 11.2mm and 20.55 ±10.92mm respectively. Statistical analysis using paired t-test indicated a significancedifference in the mean tear production (p<0.05) in the selected sample with themaximum reduction in tear production at 60 mins

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