Effect of Pack-Year of Cigarette Smoking on Erythrocyte Parameters and Glucose Level Among Healthy Males

Osamah Awad Ahmed

doi:10.12996/gmj.2017.57

Abstract

Objective: To evaluate the effect of cigarette smoking and pack-year of cigarette smoking on red blood cell counts and its related parameters, also glucose concentration. Methods: Sixty consenting subjects of which 30controls (non-smokers) and 30 cases (smokers) were studied. Smokers were divided into two groups based on pack-year of cigarettes smoked. The red blood cell parameters and glucose level were analyzed in smoker and non-smoker. Independent T-test was used to comparison of a smoker and also one way ANOVA was used to comparison pack-year of smoking groups. Results: The present study showed no changes significantly in red blood cell parameter and glucose level between in smoker. The current result appeared alteration of red blood cells counts (RBC), hemoglobin level (HGB), hematocrit percent (HCT) and mean corpuscular hemoglobin concentration level (MCHC), while no difference of mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), red cell distribution width (RDW) and glucose level in duration of smoking. Conclusions: This study revealed that cigarette smoking statistically no effect on RBC counts and its related parameters and glucose level among healthy. However, the duration of smoking statistically had the effect on RBC, HGB, HCT and MCHC while had no effect on MCV, MCH, RDW and glucose level.

Highlights

Cigarette Smoking is the most important medical problem in the world
The result was revealed that red blood cells counts (RBC), hemoglobin level (HGB), HCT were elevation as increase PackYear in smoker while Mean Corpuscular Hemoglobin Concentration (MCHC) were reduced as an increase of Pack-Year smokers
The study shows that Mean Corpuscular Volume (MCV) and Mean Corpuscular Hemoglobin (MCH) were reduced with higher of Pack-Year smokers but non-significant while red cell distribution width (RDW) and Glucose level were an increase as increase Pack-Year in the smoker but it is insignificant (Table 2)

Summary

INTRODUCTION

Cigarette Smoking is the most important medical problem in the world. The deaths of smoking are more than else illness such as an acquired immune deficiency syndrome (AIDS) and an intestinal sickness [1]. Cigarette Smoking has an effect on organ systems mainly respiratory systems and cardiovascular systems [5]. A reviewer was recommended that Cigarette Smoking influence the Parameters of the cell in blood. While some of reviewer noted the Cigarette Smoking has no effect on hemoglobin. The studies evaluated the effect of Cigarette Smoking on Red Blood Cell Parameters [16, 17, 18, 19] and Glucose levels [20,21,22,23,24,25] but they are not incontrovertible.

METHODOLOGY

RESULT

Findings

DISCUSSION