Abstract
It is aimed to study effects of origanum vulgare on serum glucose, blood film (total and differential white blood cells and immunoglobulin (IgG,IgM,IgA and complements C3 , C4) in alloxane-induced diabetic mice. Animals were divided into five groups of 5 animals each as follows: Non-diabetic mice (control group), non-treated alloxane diabetic mice, alloxane diabetic mice treated with origanum vulgare. Alloxan diabetic mice were injected with Origanum Vulgare extract for 1,2,3 weeks at a dosage of 0.18 g/kg body weight. The mice treated with alloxan (150 mg/kg B.W) to induce diabetic were showed increased in blood glucose level (hyperglycemia) , decreased in total and differential WBCs and immunoglobulin (IgG,IgM,IgA and complements C3 , C4) compared with control group, while the results of alloxan diabetic mice treated with origanum vulgare showed significantly (P<0.05) decreased in blood glucose level , increased in total and differential WBCs and immunoglobulin (IgG,IgM,IgA and complements C3 , C4) compared with alloxan diabetic mice group with out treated.
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