Effect of organic acid blend and Bacillus subtilis alone or in combination on growth traits, blood biochemical and antioxidant status in broilers exposed to Salmonella typhimurium challenge during the starter phase

Alaeldein M Abudabos,Abdullah H Alyemni,Yousif M Dafalla,Rifat U Khan

doi:10.1080/09712119.2016.1219665

Alaeldein M Abudabos, Abdullah H Alyemni + Show 2 more

Open Access

https://doi.org/10.1080/09712119.2016.1219665

Copy DOI

Abstract

ABSTRACTThe present study was designed to find the effect of an antibiotic, an organic acid and a probiotic on performance traits, blood biochemical parameters and antioxidant status during the starter phase exposed to Salmonella typhimurium challenge. A total of 300 day-old broiler chicks were randomly allocated to control (basal diet), T1: infected with Salmonella enteric subsp. Typhimurium; T2: infected + avilamycin; T3: infected + organic acid; T4: infected + Bacillus subtilis; T5: infected + organic acid + probiotic. The results showed that body weight, feed conversion ratio and production efficiency factor did not differ (P > .05) between the control and treated groups. Blood albumin and aspartate aminotransferase increased significantly (P < .05) in birds in T5 during the first week. Similarly, total protein and triglyceride concentration increased significantly (P < .05) in T4 and T5. The total antioxidant capacity in the second week decreased significantly in T4 compared to the control. Thiobarbituric acid reactive substances during the first and second weeks did not differ significantly (P > .05) between the control and treated groups. We concluded that the effect of organic acid blend and B. subtilis was similar to that of the antibiotic in broilers during the starter phase exposed to S. typhimurium challenge.

Highlights

Salmonellosis is one of the most frequent zoonotic disease caused by the bacterium Salmonella having more than 2500 serotypes (Calenge et al 2010)
Many researchers have documented that the use of Bacillus subtilis as a probiotic plays an essential role in animal performance and health by adjusting the intestinal ecological imbalance (Abudabos et al 2013; Khan & Naz 2013)
The findings of Feed intake (FI), body weight (BW), Feed conversion ratio (FCR) and PEF during the first and second weeks are presented in Tables 2 and 3

Summary

Introduction

Salmonellosis is one of the most frequent zoonotic disease caused by the bacterium Salmonella having more than 2500 serotypes (Calenge et al 2010). Some of the Salmonella stereotypes can attack domestic animals, including poultry, and can cause severe clinical signs ranging from gastroenteritis to death This bacterium can be transferred to humans through the consumption of contaminated eggs and meat and causes food poisoning (Calenge et al 2010; Bajpai et al 2012). As a result of these circumstances, the poultry researchers are focusing on the alternative to antibiotics to optimize gut health and improve animal performance (Wu et al 2011; Chand et al, 2016; Khan et al, 2016; Raza et al, 2016) One such alternative possessing growth-promoting characteristics is organic acid, which can maintain gut health and improve animal performance by balancing normal gut flora (Sultan et al 2015). Bacillus species have been considered safe in animal production and can be administered to animals as an oral dose for weight gain and feed efficiency (Wu et al 2011; Nguyen et al 2015)

Objectives

Methods

Results

Conclusion