Abstract
We wish to report the results of some experiments made to determine the effects of various organ extracts on blood regeneration in animals made anemic by bleeding. This work was begun three years ago, but the contradictory findings at different times made it seem unwise to make an earlier report.The preparations used consisted of (1) 75 per cent alcoholic extracts of the stomach, liver and spleens of calves; (2) saline suspensions of the cells of the same organs of rabbits; (3) hemoglobin solution; (4) fat-soluble non-saponifiable material from calves' livers; (5) saline extracts of these organs of rabbits which had been made anemic by bleeding.Rabbits were used in all the experiments. They were made anemic by bleeding from the heart. The blood removed constituted about 3 per cent of the body weight, about 60 per cent of the total volume. Several blood counts and hemoglobin determinations were made before the bleeding and at frequent intervals afterwards. Our interpretation of the results of the injection...
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