Abstract
The effect of pretreatment with estradiol-17beta on the testicular discharge rate of ascorbic acid and 17-oxosteroids was studied in 4 dogs treated with human chorionic gonadotropin (HCG). Animals not receiving estrogen showed a considerable discharge of ascorbic acid and secretion of 17-oxosteroids after the administration of HCG. However HCG elicited only a slight increase in testicular ascorbic acid discharge in estradiol-treated animals which was significantly lower at 15 30 and 60 minutes after administration of HCG (p<.01). The secretion of 17-oxosteroids was also significantly lower among estradiol-treated dogs compared controls (p<.01) even though a considerable overall increase was recorded. The results suggest that ascorbic acid may have a role in the production of reduced NADP by HCG-activation of glucose-6-phosphate dehydrogenase.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
