Abstract
Atomically resolved membrane protein structures provide information on the protein's function. To obtain atomically resolved structures of membrane proteins, high quality protein crystals are required. Membrane proteins are not straightforward to crystallize; only ∼150 membrane proteins structures are known as compared to ∼20,000 for soluble proteins. Their importance is highlighted by the fact that at least one third of genes in yeast and multicellular organisms encode membrane proteins. To both extract membrane proteins from their native environment as well as stabilize monomeric dispersions of the proteins in water it is necessary to use detergents.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.