Abstract
Ocimum sanctum L., sometimes referred to as Tulsi in various Indian languages or Holy Basil in English, is a significant medicinal herb used in Southeast Asian traditional and folk medicine. It has been demonstrated via scientific studies to have immunomodulatory, anti-inflammatory, antidiabetic, hypolipidemic, antipyretic, analgesic, hepatoprotective, and stress-relieving properties. Studies have also demonstrated that Tulsi and some of its phytochemicals—including eugenol, apigenin, myretenal, sitosterol, rosmarinic acid, carnosic acid and luteolin—prevent chemically induced oral, gastric, cervical, skin, liver, and lung cancers. These effects are mediated by increased antioxidant properties, inhibition of angiogenesis and metastasis, induction of apoptosis and altered gene expressions. This chapter summarises findings about the chemopreventive effects of Tulsi on various malignancies and also highlights elements that call for more investigation to confirm the herb's efficacy and value in the treatment and prevention of cancer.
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