Effect of obstructive sleep apnoea on neurological recovery after acute ischemic stroke

Abstract

Introduction: The presence of obstructive sleep apnoea (OSA) has been found to adversely affect the neurological recovery after acute ischemic stroke (AIS). Aims and Objectives: The aims of this study were to investigate the prevalence of OSA in patients with AIS and to compare the functional outcome in those with and without OSA. Methods: A prospective single center study was conducted at Kyungpook National University Hospital. Patients with AIS and TIA were included. Subjects completed questionnaires including Korean version of the Berlin Questionnaire (BQ-K), Epworth Sleepiness Scale (ESS-K), and Pittsburgh Sleep Quality Index (PSQI-K). The prevalence of OSA was assessed by the Sleep Obstructive apnea score optimized for Stroke (SOS score). The functional outcome was assessed by modified Rankin Scale (mRS) at 3 months after AIS. Results: A total 238 (mean age was 63.7 ± 12.4, males; 65.5%) patients were enrolled. OSA according to the SOS score was 64 patients (26.9%). Patients with OSA had a significantly higher proportion of poor sleep quality than those without OSA (p Conclusions: This study showed that AIS with OSA tend to have poor sleep quality and functional recovery.