Effect of Obesity on Thyroid Stimulating Hormone Levels at Atbara Town, Sudan

Abstract

Background: Obesity is a condition of excess adipose tissue associated with hormonal imbalances associated with the degree of obesity. Objective: To assess the effects of obesity on thyroid-stimulating hormone in Sudanese subjects in Atbara, Nile State. Materials and Methods: Collect 40 samples from randomly selected obese and overweight (male and female) subjects in Atbara City, Nile State. Between July and September 2021. Efficacy was evaluated in 20 healthy subjects with normal BMI of TSH levels of obesity as a control group. Serum TSH levels were determined using an enzyme immunoassay analyzer (TOSOH) and results were analyzed using the Social Science Statistical Package (SPSS) computer program. Results: The results of this study showed the mean concentration of TSH levels in obese subjects (mean ± SD) (1.248 ± 0.48915) and controls (1.480 ± 0. 3), P. value = 0.07 and was also non-significant. Also showed that the mean concentration of BMI, waist circumference and waist hip ratio and TSH level was (33.58,106.187,1.07,1.24) with P. value (0.063,0.404,0.064,0.860) respectively, which is insignificantly. Conclusions: Obesity has no effect on TSH levels, and it is concluded that there is no correlation between BMI, waist circumference, waist-to-hip ratio, and TSH levels.