Abstract
This was a retrospective study of 120live kidney donors (75females, 45males). GFR was evaluated from 51Cr-EDTA plasma clearance using blood samples taken at 3, 4 and 5hours. The slope-intercept GFR was corrected for body surface area using the Dubois & Dubois and for the fast exponential using the Brochner-Mortensen equation. Scatter plot of DFG against age in live kidney donors was plotted and the 98% range limits have been defined. The median GFR obtained for kidney donors was 88mL/min/1.73m2 [68-130]. No significant difference with gender was found. 51Cr-EDTA clearance was strongly correlated with patient age (r =-0.62, P <0,0001). GFR decreased by approximately 8mL/min/1.73m2 per decade. Based on these results, a nomogram for GFR is presented. The interpretation of GFR requires age-adjusted normal values. These standards need not be adjusted to the patient's sex or BMI.
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