Effect of nursing intervention based on chronotherapeutics on blood pressure and medication compliance of patients with hypertension

Abstract

Objective To explore the effect of nursing intervention based on chronotherapeutics on blood pressure and medication compliance of patients with hypertension .Methods One hundred and twenty-six patients with hypertension in outpatient from August 2012 to February 2013 were chosen and divided into the control group （ n=60） and the intervention group （ n=66） according to the random number table .The control group received the routine health education , and the intervention group received the nursing intervention based on chronotherapeutics .The blood pressure and medication compliance were compared between two groups . Results No differences were found in the systolic blood pressure （SBP） and diastolic blood pressure （DBP） between two group before intervention （P>0.05）.After intervention, the SBP was （134.3 ±5.54） mmHg in the intervention group, and was （143.4 ±7.93）mmHg in the control group, and the difference was statistically significant （t=-3.596,P〈0.01）; the DBP was （84.8 ±3.81） mmHg in the intervention group, and was （90.7 ±5.07）mmHg in the control group, and the difference was statistically significant （t=-3.622,P〈0.01）.After intervention, the score of medication compliance was （2.8 ±0.81） in the intervention group, and was （2.0 ±0.77） in the control group, and the difference was statistically significant （t=5.267,P〈0.05）. Conclusions The nursing intervention based on chronotherapeutics can effectively control the blood pressure , and improve the medication compliance of patients with hypertension , and it should be recommended to other hypertension patients . Key words: Hypertension; Intervention research; Chronotherapeutics; Compliance