Effect of Non-Computerized Cognitive Remediation and Risperidone to Improve Disability Function in Schizophrenia

Abstract

The aim of the study was to find out the effect of non-computerized cognitive remediation and risperidone therapy to improve cognitive function and disability condition in schizophrenia patients. This study was an experimental research design, with fourteen participants divided into two group as the experimental group and the control group. The experimental and control groups both received Risperidone. In addition, the experimental group was given the non-computerized cognitive remediation (CR).The non-computerized cognitive remediation will be carried out in 12 sessions (3 sessions per week) using mainly paper and pencil tasks and is based on cognitive strategy instruction. Moreover, all samples will be measured for PANSS (Positive and Negative Symptom Scale), WHODAS 2.0 (World Health Organization Disability Assessment Schedule), and SCoRS Vi (Schizophrenia Cognition Rating Scales Indonesian Version) scores. As the results, both experimental and control group showed a significant decrease in the SCoRS Vi and WHODAS 2.0 score (p=0.001). However, the experimental group showed greater improvement compared to the control group. Synergistic effect of Non-computerized Cognitive Remediation and Risperidone can improve disability condition in schizophrenia patients.