Abstract
The effect of extracts of Nigella sativa seeds against some clinically important actinomycetes namely: Gordonia, Mycobacterium, Nocardia and Rhodococcus were investigated. Petroleum ether extract of N. sativa seeds was found to be more effective than methanolic extracts. At 0.3 mg/ml, 0.5 cm inhibition zone was noticed in all test strains except Rhodococcus rhodochrous. Variable inhibition zones were shown by test strains to other concentrations used. The study concluded that petroleum ether extract of N. sativa is a promising candidate for further in vitrotesting and in vivo application as well. It is a recognized traditional healing and food additive seeds in many cultures with no reported harmful effect. Key words: Nigella sativa, actinomycetes, antibacterial agents.
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