Abstract

AbstractACTH, 50, 10, 2 and 0.5 IU/kg b.w. and noradrenaline, 1.0 μg/kg/min were given i.v. to fed, unanesthetized rabbits either pretreated with nicotinic acid or not.Both ACTH and noradrenaline increased arterial concentration of free fatty acids (FFA). For noradrenaline this effect was present only in rabbits with lower body weight and furthermore the effect was less pronounced and of shorter duration than for ACTH.Nicotinic acid inhibited partly the increase of plasma FFA caused by 0.5 IU of ACTH but not that after the higher doses. Nicotinic acid had sometimes but not always an inhibitory effect on the increase caused by noradrenaline while nicotinic acid by itself did not change the basal levels of plasma FFA.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.