Abstract
Effect of Nicotine on Hematology, Lipid Profile and Liver Enzymes in Adult Male Mice (Mus Musculus)
Highlights
Nicotine is thought to be the main component present in the smoke of tobacco, which works as a neuro–toxic and largely accounts for most of the deleterious effects (Slotkin, 2004)
The main aim of the present study was to study the influence of nicotine on various hematological parameters, lipid profile and liver enzymes in adult albino mice
During the 6 weeks of experimental period it has been observed that the food intake as well as body weight of experimental mice was decreased as compared to the control group (Figure 2 and 3)
Summary
Nicotine is thought to be the main component present in the smoke of tobacco, which works as a neuro–toxic and largely accounts for most of the deleterious effects (Slotkin, 2004). Changes in the hematological parameters due to the inhalation of nicotine may be an important reason for various vascular diseases. Inhalation of considerable concentration of nicotine cause alternations in various hematological parameters, including white blood cells, mean corpuscular volume, hematocrit, hemoglobin, monocyte, eosinophil, neutrophil and lymphocyte counts (Bain et al, 1992). The main aim of the present study was to study the influence of nicotine on various hematological parameters, lipid profile and liver enzymes in adult albino mice
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