Abstract

25Aug 2019 EFFECT OF NEOADJUVANT CHEMOTHERAPY ON HORMONE RECEPTOR (ER, PR) STATUS AND HER-2/NEU EXPRESSION IN INDIAN BREAST CANCER PATIENTS: A PROSPECTIVE STUDY. Saumya Singh , Vaibhav Jaiswal , Anand Kumar Mishra and Sandeep Tewari. Department of General Surgery; Department of Trauma Surgery; Department of Endocrine Surgery, King George`s Medical University, UP, Lucknow, India.

Highlights

  • (n=49) were Progesterone receptor (PR) before treatment which increased to 71.8% (n=51) post chemotherapy (p=0.99)

  • Change in expression of hormone receptor status was noticed, Estrogen Receptor (ER)+PR+ decreased to 25.4% (n=18), ERPR- increased to 69.0% (n=49), ER-PR + decreased to 2.8% (n=2), no change was noticed in ER+PR- status

  • Her-2/neu status changes on IHC staining after neoadjuvant chemotherapy (NACT)

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Summary

RESEARCH ARTICLE

EFFECT OF NEOADJUVANT CHEMOTHERAPY ON HORMONE RECEPTOR (ER, PR) STATUS AND HER-2/NEU EXPRESSION IN INDIAN BREAST CANCER PATIENTS: A PROSPECTIVE STUDY.

Objective
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