Effect of negative pressure incision care dressing on wound infection rate in colorectal surgery: A prospective non randomized trial

Abstract

s / International Journal of Surgery 12 (2014) S13eS117 S34 1056: EFFECT OF NEGATIVE PRESSURE INCISION CARE DRESSING ON WOUND INFECTION RATE IN COLORECTAL SURGERY: A PROSPECTIVE NON RANDOMIZED TRIAL Syed Muhammad Amir Zaidi, Wasif Majeed Chaudhry, Haseeb Anwar Khokhar, Hamid Majeed, Suhail Aslam Khan. Our Lady of Lourdes Hospital, Drogheda, Co Louth, Ireland. Introduction: Negative Pressure Incision care therapy (NPICT) has never been reported in colorectal surgery. The aim of this trial is to evaluate the effect of NPICT on wound infection rate. Methods: 317 consecutive patients underwent major colorectal procedures in a regional hospital over 3 years by a single team. 104 (32.1%) patients were excluded on the basis of other complications affecting LOS. Out of 213 patients included, 71 (33.3%) patients received NPICT, while 142 (66.6%) patients received regular dressings (Non-NPICT group). Study endpoints were rate of 30-day wound infection rate and LOS. Results: The mean age was 66.46 (NPICT) and 65.58 (Non-NPICT). Male to female ratio was 1:1.06(NPICT) and 1:1.04(Non-NPICT). Patients in NPICT group underwent at least 07 days of incision care therapy. 3 patients (4.2%) in NPICT group and 29 patients (20.4%) in Non-NPICT group developed wound complications [p 250pmol/L) leading to higher urinary losses of potassium (p1⁄40.03) and creatinine (p1⁄40.01). 19 patients 32%) demonstrated postprandial hypoglycaemia( 2 major system disorders in 21(16%) patients. Common referral sources to the MDT were surgical out-patients (42%), and endoscopy (13%). The average lead time from referral to index MDT discussion was 14-days. In phase II, ACE27 was administered in 50-patients, mean age-54-years (range 20-84). Male: female ratio 26: 24. Average time to administer ACE-27 was 4.8minutes (range 1-15). Conclusions: The phase I study confirmed the previously widely acknowledged view of poor co-morbidity data availability within a CRC