Effect of needles distance of arteriovenous fistula cannulation on hemodialysis adequacy based on KT/V: a randomized controlled trial.

Abstract

This study aims to assess the effect of needle distance of arteriovenous fistula (AVF) cannulation on haemodialysis adequacy based on KT/V. This study was a parallel-group, randomized controlled trial. Patients who met the inclusion criteria were divided into two groups with 3 and 6cm needle distances using block randomization. Data acquisition transpired through a comprehensive checklist encompassing demographic variables such as age and sex, alongside clinical metrics comprising actual weight, dry weight, average dialysis duration, fistula longevity, and KT/V rate. A total of 42 haemodialysis patients were enroled in this investigation, with 21 allocated to the 3cm needle distance group and another 21 to the 6cm needle distance group. The mean post-haemodialysis KT/V values for the 3cm and 6cm needle distance groups were 1.25 (SD=0.25) and 1.42 (SD=0.24), respectively, demonstrating a statistically significant difference (P<0.001). While there was no significant difference in the average pre-haemodialysis and post-haemodialysis KT/V values within the 3cm needle distance group (t=1.93, P=0.068), the corresponding values for the 6cm needle distance group exhibited a notable discrepancy (t=9.66, P<0.001). In general, a needle distance of 6cm between arteriovenous points yielded superior enhancements in dialysis adequacy compared to a 3cm needle distance following haemodialysis. Consequently, health administrators and policymakers may consider instituting efficacious interventions to scrutinize the care and therapeutic protocols for haemodialysis patients, involving the development of policies and applications.