Effect of nanopore size on poly(dT)30 translocation through silicon nitride membrane

Abstract

The nanopore size effect on translocation of poly(dT)30 through Si3N4 membrane is investigated. In this paper, we report that the speed of the poly(dT)30 transport through Si3N4 nanopores can be slowed down by half through increasing the nanopore diameter from 4.8 nm to 10.8 nm. The results are consistent with our simulation results. Besides, the current blockage induced by DNA passing through the nanopore is less obvious as pore diameter is larger, which is in good agreement with the theoretical prediction. The conclusion about DNA transport through nanopores is beneficial for the design of DNA sequencing devices.