Abstract

In experiments on the kinetics of strand breakage of bacterial DNA in a uvrC mutant, it was shown that the results are similar to those described earlier for the breakage of superinfecting lambda DNA. In the first several minutes after irradiation, more breaks appear in a uvr strain than in the uvrC mutant, but at later times the situation is reversed. The action of the uvrC gene product may be to interfere with the joining by polynucleotide ligase of the break made by the uv endonuclease. (HLW)

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