Abstract
To identify whether muscular exercise increases the plasma concentration of uridine and of purine bases, the effect of rigorous muscular exercise was determined in five healthy men with a bicycle ergometer. Twenty-five—minute muscular exercise at 65% maximum O 2 consumption increased the concentration of uridine, purine bases, and inorganic phosphate in plasma and of NH 3 and lactic acid in blood. These results suggest that exercise-induced excessive adenosine triphosphate (ATP) consumption enhanced not only purine degradation but also pyrimidine degradation (uridine triphosphate [UTP] → uridine diphosphate [UDP] → uridine monophosphate [UMP] → uridine) in exercising muscles.
Published Version
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