Abstract
This study assessed the osteogenic effect (T-Score) and changes in bone markers in healthy subjects by 12-weeks of aerobic training. Total 65 healthy subjects (36 males, 29 females), their age ranged between 30 and 60 years with normal body mass index, were recruited to participate in this study and they were selected among healthy subjects who do not have any metabolic disorders and were not receiving any medication that could affect the bone turnover. Standardized physical examination and collection of serum samples were performed at base line and after 12 weeks of moderate aerobic training to measure bone formation markers (osteocalcin (OC) and bone specific alkaline Phosphatase (BAP) and bone resorption marker Deoxypyridinoline (DPD), and serum calcium. Each subject participated in exercise training program for 12 weeks, three times per week. The results showed that the 12 weeks of moderate aerobic training produced a significant improvement in all bone metabolism indices including Serum bone-specific alkaline phosphatase, serum osteocalcin, serum free Calcium and bone mineral density among all subjects. Conclusion : Moderate intensity of aerobic training exerts significant positive effects on bone formation marker and bone density associated with a significant decrease in the rate of bone resorption that could assist in preventing or decelerating osteoporosis.
Highlights
Bone is a specialized form of metabolically active connective tissue remodeled constantly through a coupled process of resorption and the formation of new bone
The results showed that the 12 weeks of moderate Arabic training produced a significant improvement in all bone metabolism indices among subjects as shown in Tables II, III and Fig.[1] and Fig.[2]
This investigation examined the effects of moderate aerobic exercise on bone mineral density (BMD) and biochemical markers of bone turnover in healthy elderly subjects
Summary
Bone is a specialized form of metabolically active connective tissue remodeled constantly through a coupled process of resorption and the formation of new bone. There was haemostatic equilibrium in bone resorption and formation around age 30, after which bone density starts to decline slowly.[1]. Exercise is a major determinant of bone mass; the mechanisms by which exercise leads to changes in bone metabolism are not fully understood. Little is known about the changes in bone metabolism induced by various forms of systematic exercise.[2] The benefit of mechanical loading or exercise on bone mass and strength has been identified in both human,[3] and animals’ models.[4] High intensity of exercise as jumping or resistive
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