Effect of Mobile Radiation and Diabetes on Pituitary-Gonadal Axis Function in Adult Male Rats

Abstract

Aims: The potential risk of radiations caused by the mobile phones affecting human, as well as the prevalence of diabetes, are of the main concerns in developing and modern societies. The aim of this study was to investigate the effects of radiations caused by the mobile phones on the serum level of sexual hormones in streptozocin-induced diabetic adult male rats. Materials & Methods: In the experimental study, 64 Wistar adult male rats were studied. The rats were divided into 8 groups (n=8 per group) including non-diabetic control, diabetic control, and 6 experimental groups. Control groups received no treatment. Diabetic experimental groups underwent 7-day continuous and cutoff mobile radiations and buzzer sound. At the end of the course, blood sampling having been done, serum levels of LH, FSH, and testosterone were measured. Data was analyzed by SPPS 18 software using one-way ANOVA and Tukey’s post-hoc. Findings: Diabetes alone and with continuous and cutoff radiations of the mobile phones and buzzer sound led to a reduction in testosterone level (p<0.05). Diabetes had no effect on LH and FSH. Nevertheless, 2-hour cutoff radiations of the mobile phones led to a significant increase in FSH in the diabetic rats (p<0.005). In addition, 1-hour and 2-hour continuous radiations and 2-hour cutoff radiations of the mobile phones led to significant increases in LH in the diabetic rats (p<0.05). Conclusion: In adult male rats, diabetes, radiations of mobile phones and buzzer sound lead to testosterone reduction. In addition, diabetes with mobile phone radiations leads to increases in LH and FSH levels.