EFFECT OF METFORMIN ON WEIGHT REDUCTION AMONG DIABETIC AND NON-DIABETIC OBESE PATIENTS

,Hanin F Hussin,Iman E Mohamed,Sanad W Alobidy,Fatma M Bosafita,Pharmd, Faculty Of Pharmacy, Libyan International Medical University, Benghazi, Libya

doi:10.21474/ijar01/12531

Abstract

Context: Metformin is the first line treatment in type II diabetes mellitus. In addition, it was used for weight reduction in both diabetic and non-diabetic obese patients. Aims: The aim of this study was to examine the efficacy of metformin in weight reduction among diabetic and non-diabetic obese patient in Benghazi, Libya. Settings and Design: a cross-sectional study Methods and Material: A hundred well-designed a cross-sectional survey was distributed from January to December 2020 and filled by diabetic and non-diabetic obese patients (66 and 34, respectively) in Benghazi city. Statistical analysis used: SPSS statistics soft wear (Version 21.0 SPSS Inc.: Chicago, IL, USA). Results: Results had shown that 66.7 % of diabetic obese patients were more than 50 years while 35.5 % of non- diabetic obese patients were 21-25 years. 1-5 kg was the weight reduction in both diabetic and non-diabetic obese patients (43.9 % and 38.2 %, respectively) Conclusions: According to this study, metformin is an eï¬€ective therapy to reduce weight in diabetic and non-diabetic obese patients. Further studies are needed with exact weight reduction.

Highlights

Results had shown that 66.7 % of diabetic obese patients were more than 50 years while 35.5 % of non- diabetic obese patients were
Thirty-four obese females who used metformin for the purpose of losing weight were included in this study, whether the weight gain was a result of diseases such as polycystic ovary syndrome (PCOS) or without a specific disease
The majority (66.7 %) of diabetic patients were more than 50 years and 22.5 % were 46-50 years while the majority (35.5 %) of non- diabetic patients were 21-25 years old followed by 25.5% were 32-35 years (Table.1)

Summary

Manuscript History

Context: Metformin is the first line treatment in type II diabetes mellitus. It was used for weight reduction in both diabetic and non-diabetic obese patients. Aims: The aim of this study was to examine the efficacy of metformin in weight reduction among diabetic and non-diabetic obese patient in Benghazi, Libya

Methods and Material

Results

Conclusions

No age group

No change weight increase